Power and sampleizde calculator for genetic association studies

Models

SNP or Haplotype

Genetic Model

Disease prevalence

D prime for LD

Marker allele frequency

Disease allele frequency

Disease haplotype frequency

Number of haplotypes

Parameters

Power or Sample size

Number of cases

Significance level

Power of test

Relative risk

Relative risk RR2

Total number of SNPs

Control/case ratio

Summary

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Reference:

Menashe, I., Rosenberg, P. S. and Chen, B. E., (2008). PGA: power calculator for case-control genetic association analysis. BioMed Central (BMC) Genetics. 9, 36.

This app is created by Bingshu E. Chen, Ph. D., Canadian Cancer Trials Group , Professor, Department of Public Health Sciences, Queen's University, Kingston, Canada. Link to this app, http://statapps.tk/pga

Acknowledge: The web portal is supported by Virtual Machine from Compute Canada Cloud service.

Created: August 29, 2016.

Revised: Septermber 20, 2020.

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